Will Goldenseal Help Pass A Drug Test?

Daniel Miller avatar
Daniel Miller, Ph.D, Drug Testing Specialist

Last updated on Jul 18, 2023

Goldenseal can be used to pass a drug test in three ways.

Goldenseal slows the activity of drug-metabolizing enzymes in the liver. Thus if you take Goldenseal before the drug test, fewer marijuana metabolites will be excreted into the urine.

Taking Goldenseal can help to detox from marijuana faster and pass a drug test. It helps to improve fat breakdown and release marijuana metabolites for excretion.

Adding Goldenseal to urine can give a false negative too. But this method is illegal.

We’ll explain how Goldenseal helps detox from THC faster and provide step-by-step instructions on using it.

How Does It Work

Goldenseal is a medicinal herb grown mainly in the North-Eastern U.S. and Southern Canada, belonging to the buttercup family.

Traditionally, Goldenseal has a wide reputation for treating infections, digestive disorders, and inflammatory conditions.

We will share how Goldenseal will or will not help in giving false-positive results in your drug testing.

Goldenseal Helps in Weight Loss

The main active ingredient of Goldenseal is berberine.

Most of the marijuana metabolites (THC and others) are stored in body fat, so you need to break down that fat cells to release THC for excretion.

Several studies were done to show how berberine affects the breakdown of fat.

An animal study showed that berberine helps in reducing diet-induced obesity as well.

However, the results from the study show that berberine prevents obesity from the diet. It means that the subject lost weight after giving a fat-based diet.

That doesn’t relate to the body fat that the subject already has. So it didn’t prove that berberine burns fat and releases the THC present inside it.

But several other studies prove how berberine acts as an essential weight loss agent.

For example, a 12-week study on obese individuals showed that berberine helped reduce 3.6% of total body fat.

In another study, when taken for 3 months, berberine helped cut down weight and body fat in metabolic syndrome patients.

The researchers concluded that berberine improves the functioning of insulin and fat-regulating hormones to reduce weight.

Impressively, some studies proved how berberine inhibits fat cell growth. Others showed how it helped in elevating fat-breaking processes indirectly.

Due to berberine’s weight-losing properties, we can relate that Goldenseal may burn fat to detox THC. However, further studies are needed to prove that fully.

Overcoming the slow THC metabolism

Goldenseal slows the activity of several liver enzymes, including CYP2C19, CYP2C9, CYP3A4. All 3 of them are involved in metabolizing THC during phase 1.

By inhibiting them, Goldenseal slows down the excretion of THC metabolites through urine and feces.

This effect is helpful if used on the day of the test. Taking Goldenseal on the day of the test will reduce the number of marijuana metabolites excreted into the urine.

Thus the concentration of THC metabolites in the urine will drop below the detectable level.

However, this effect is bad if your goal is detoxification from marijuana. But you can overcome it by taking St. John’s wort with Goldenseal. This will induce or enhance the activity of liver enzymes required for THC metabolism.

Thus, it will prevent Goldenseal from slowing down your THC’s metabolism, required for detox.

Goldenseal Acts as a Diuretic

Goldenseal is famous for its diuretic property. It will help you urinate more and excrete out THC metabolites through flushing.

So, you need to drink enough water to dilute your urine and pee enough before the test.

Goldenseal May Prevent The Sticking Of THC To Urinary Walls

Goldenseal contains isoquinoline alkaloids. Among many, berberine is thought to prevent the sticking of E.coli. These bacteria cause urinary infections to the urinary tract walls.

Similarly, Goldenseal is believed to prevent the sticking of THC metabolites to the urinary tract walls and enhance its flushing. However, you won’t find any scientific explanation to prove this assumption.

Adding Goldenseal Directly To Your Urine

A study claims that adding Goldenseal directly to urine helped in giving false-negative results through fluorescence polarization immunoassays.

However, practically it won’t work as a concentration of 0.9% was used as a sample, i.e., one capsule mixed with 60ml urine.

Ideally, you would need that exact concentration to achieve the results as Goldenseal is insoluble at higher concentrations. Plus, the urine volume taken for drug testing varies from place to place.

Thus, practically it’s impossible to estimate the correct concentration every time.

Most importantly, this method is illegal. Also, today, drug testers use special lab techniques to detect Goldenseal in urine, which is recognized as an adulterant.

Therefore, we recommend you not to try this method as it will get you caught.

How To Use Goldenseal to Detox from THC and Pass a Drug Test

There are two methods to pass a drug test with Goldenseal. You can either use it as a detox or as a same-day solution for flushing out THC.

Make sure you are using original and authentic goldenseal products for your detox. Fake products having low-quality fillers like starch may negatively interfere with the methods.

Depending on your choice, you can either use goldenseal tea, gargle, or capsules. Each will give you similar results.


Goldenseal detox

Same-day solution


Method 1: Goldenseal Detox

If you want to detoxify THC, we recommend adding St. John’s wort. As mentioned before, this step will save your THC from slow metabolism from Goldenseal and hence enhance detox.

  1. Make your goldenseal tea by boiling one cup of water.
  2. Add a teaspoonful of goldenseal powder to a cup and pour the hot water on it.
  3. Mix well and allow the mixture to steep for around 20 minutes.
  4. Cover the cup with a lid to avoid the escape of heat.
  5. Strain this tea and add honey or lemon for taste (optional).
  6. Drink it while it’s hot and take one 300 mg tablet St. John’s Wort.
  7. You can either consume 2-3 goldenseal tablets or use a tincture for gargles as an alternative to tea. For gargling, dilute 1-1½ teaspoonful of goldenseal tincture in a cup of water and gargle for two minutes.
  8. Repeat the process 2-3 times a day for one week.
  9. Stay hydrated and urinate throughout the week.

You can start this method a week before your test. Avoid taking any other drug during the period.

Taking Goldenseal for more than a week can cause side effects.

But if you are allergic to St. John’s wort or want a temporary solution for your test, you can try the other method.

Method 2: Same-day solution

Consuming Goldenseal on the same day with plenty of water will help flush out THC through your urine. Its diuretic properties will help you dilute urine and pee more.

But you need to add other ingredients like creatinine, salt, and vitamin supplements to restore the natural urinary parameters.

  1. Take goldenseal (tea/capsule/gargle) 2 hours before the test.
  2. Add one vitamin-B complex tablet, 5g creatinine, and a bit of salt for electrolytes.
  3. Drink enough water (2-3 liters), and urinate thoroughly before the test.

Helpful Tips

Drink enough water throughout the methods and pee frequently. It will dilute your urine and help you excrete THC faster.

Some people may be allergic to Goldenseal. So, if you start noticing allergic reactions like skin rash and shortness of breath, for example, stop the method immediately.

Plus, if you are pregnant or breastfeeding, these methods are not for you.

Side effects


These methods are not much reliable because it depends on a different personal factors, including:

Amongst the drawbacks of the goldenseal method is the need to ensure purchasing original herb; not adulterated with other filler ingredients, such as starch that is 100% useless, in regards to drug tests.

That’s why you need to ensure purchasing from a reputable seller.


Goldenseal may help you detox and/or flush out your THC to pass the drug test.

As a diuretic, Goldenseal increases urination and produces more dilute urine when taken with water. But it will not mask your THC metabolites.

Its active compound, berberine, has fat-burning properties. Due to this, Goldenseal can detox THC by burning fat.

But due to enzyme inhibition, Goldenseal can slow down the detoxification process.

So, using it with an enzyme inducer like St. John’s wort or a same-day solution may compensate for the problem.

Adding a goldenseal capsule directly to the urine sample (60 ml) has given false-negative results too. But this method is illegal and may get you caught due to special testing.

Thus, Goldenseal can help you pass your drug test. However, the results may vary from person to person. Plus, you can’t use these methods if you are pregnant or allergic to Goldenseal.

100% Success Rate for Passing Drug Tests!

Clear Choice Sub-Solution is the perfect solution for passing a drug test. It contains a clean synthetic urine that is biocide free and completely undetectable.

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Furthermore, the standard size container makes it easy to conceal, and it is unisex, so it can be used by both male and female users.

The information on this website about detox products and synthetic urines is for educational purposes only. We do not endorse or condone their illegal use. Always consider the laws in your area and the potential legal consequences. Consult with a healthcare professional before using any products. Your responsibility and well-being are paramount.