The list of vitamins that will help you pass a drug test

Vitamins and minerals have a significant contribution in the detoxification of drugs such as THC in the body. They do this by supporting and offering a conducive environment for the proper functioning of the liver and kidneys ­ the two major organs responsible for detoxification.

However, despite their well-documented roles in the detoxification process,  there’s no single vitamin that can help ‘clean’ your urine by removing drug metabolites in readiness for an upcoming urinary drug test .

That does not necessarily mean that vitamins have absolutely no place in passing a urine drug test though.

In this article, I’ll be explaining two ways through which vitamins can help in passing a drug test: vitamins that provide diuretic effect and vitamins that complement the dilution method.

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Vitamins with diuretic effects

Also known as a ‘water pill’, a diuretic is anything that causes the body to increase the amount of water and salt excreted through the kidneys as urine.

Diuretics mainly come in the form of detox pills although several other substances produce these effects including cranberry juice, coffee, tea, and alcohol. Some vitamins are also known to make the body lose more water.

A vitamin with diuretic effects helps in passing a urine drug test by increasing the amount of water in the urine, thereby lowering the concentration of drug metabolites in the urine sample to below the cutoff level.

This is to say that the metabolites are still present in your system only that their number in the urine sample has been diluted by the additional amount of water.


Vitamin C

Also known as Ascorbic acid, vitamin C is currently being studied for its ability to treat certain diseases and conditions such as high blood pressure. An analysis of research results by the Johns Hopkins University School of Medicine suggests that vitamin C may lower high blood pressure due to its diuretic effects.

This vitamin causes the kidneys to excrete more water and sodium from the body. As a result, the blood vessel walls relax thereby lowering the blood pressure.

Edgar R. Miller, M.D, Ph.D., who is an associate professor at the Johns Hopkins University says that one needs to  take at least 500mg of ascorbic acid to experience its diuretic effects. 

In another 1936 study on the diuretic action of vitamin C recorded in the National Institutes of Health, an increase in the level of urine was evident after the subjects were a given a dose of 700mg of vitamin C for every ten stone of total body weight.

How much vitamin C should you take when relying on its diuretic effects to cheat a urine test?

Unfortunately, there isn’t an agreed gold standard amount for everyone. This is because there isn’t a lot of studies that have been conducted regarding using vitamin C to cheat a test.

On this note, I highly believe that this would greatly vary from one person to the other depending on the concentration of THC metabolites in their urine.

Speaking to Mayo Clinic, Katherine Zeratsky advises taking 65-90 mg daily but she also offers an upper limit of 2,000 mg. She continues to say that, while vitamin C is unlikely to cause adverse side effects when taken in higher doses, a mega-dose of it can lead to effects such as insomnia, heartburn, diarrhea, vomiting, headache, and abdominal cramps.

Vitamin B-6

Vitamin B6 is also known as pyridoxine and it’s vital for normal development of the brain besides keeping the immune and nervous systems healthy.

In addition to its major roles, vitamin B6 has in the most recent past been found to offer relief to people with water retention issues. It does this by correcting low thyroid function which is known to lead to low temperatures and water retention in a result.

Experts recommend taking a supplement of 500mg of pyridoxine to decrease water retention.

Vitamins that complement the dilution method

The dilution method is a sure-fire way of passing a urine drug test. It simply involves taking a lot of water in the hours leading to a drug test. As a result, a lot of water is excreted as urine thereby leading to a lower concentration of drug metabolites in the urine.

Unfortunately, the concentration of drug metabolites isn’t the only thing that is affected by consuming a copious amount of water. It also affects several other key characteristics of ‘normal’ urine including color, creatinine levels, and specific gravity.

Abnormal ranges of these parameters are the major telltales of a diluted urine when the lab experts are carrying out a test on a urine sample.

The normal color of urine ranges from yellow to deep amber. If you have used the dilution method, it’s advisable that you  take 200mg of Vitamin B2 or B12 one hour before the test to give your urine its normal color .

Creatinine is a waste product of the normal breakdown of muscle tissue. As creatinine is broken down, it is filtered by the kidneys for excretion through urine. The normal creatinine levels in urine vary from one person to the other depending on their muscle mass (the more muscle mass, the higher the creatinine levels and vice versa).

Generally, the normal creatinine values range from 20 to 370 mg/dL in men and 20 to 320 mg/dL in women.

Dilution affects the concentration of creatinine levels in the urine. In case you’ve diluted these values to below 20 mg/dL, the cutoff level for most laboratories, your sample is flagged immediately and subjected to more tests. That’s why it’s important to measure these levels before diluting to ensure that you are within the required range.

As you can imagine, it’s easy to dilute urine without getting the creatinine levels to below the cutoff mark if you are starting at a higher level. On the other hand, it can be a real challenge to maintain these values especially if you have a very high concentration of drug metabolites that you need to dilute and low creatinine levels.

In that case, it might be important to throw a supplement of creatine into the mix. Creatine supplement is mostly used in the gym since it acts as fuel for the muscles. It works by boosting the production of energy thereby leading to the release of more creatinine which is filtered into the urine.

Final Thoughts

While no vitamin is a silver bullet for beating a urine drug test, vitamin B6 and B12 or B2 can increase your odds through internal dilution and adding color to a diluted urine sample respectively.

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