How much Zinc to take to pass a drug test?

Daniel Miller
Daniel Miller, Ph.D, Drug Testing Specialist

Last updated on Apr 8, 2024

Taking 400mg pills of Zinc sulfate supplements 12-18 hours before your drug test can help you pass it. Zinc helps in masking the THC metabolites in your urine, giving it a false-positive result.

However, Zinc is not known to detox THC from your body. Plus, this method is not very reliable for regular/heavy smokers.

Adding Zinc directly to your urine can help you pass a drug test for marijuana too. It gives a false-negative result to your drug test. But this method is illegal and can cause suspicion.

We’ll explain how much Zinc you need to take to pass your drug test.

How Does Zinc Affect Drug Tests

To pass a drug test with Zinc, two methods are generally employed. The first is to consume Zinc sulfate supplement pills before the test.

The other is by adding Zinc into the urine sample. The former method is safer than the latter.

Consuming Zinc Supplements Before Test

A study published in 2011 in the Journal of Analytical Toxicology showed how ingestion of Zinc prevents THC detection.

This study was based on the enzyme-linked immunosorbent assay (ELISA) method for drug testing.

This test was done on 4 individuals. Each was given 0.75-1g of marijuana before the test. They were later given 4 zinc sulfate supplements each. Each tablet was 50 mg. So in total, each person consumed 250 mg of zinc supplements.

After collecting urine samples from these volunteers, it was interpreted that Zinc gives a false-negative result through the ELISA drug test. However, the actual science behind this result is not yet evident.

But according to an assumption, Zinc binds to THC metabolites. As a result, it produces complexes that are too large to be eliminated through the urine.

Thus, they travel through the fecal route.

However, this is not true in actuality, as the complex will still be small enough to pass through the urinary filters and be excreted with the urine.

It’s worth noting that Zinc only interferes with cheap tests that rely on the immunoassay method. It won’t interfere with the performance of GC-MS (Gas Chromatography-Mass Spectrometry) tests.

Luckily, most labs will only resort to the GC-MS screening method to confirm and quantify if the results are positive for any drug. This means that if you are lucky to circumvent the immunoassay test, you’ll be on the safer side since no confirmative tests are done.

Since the test was done on individuals consuming a small amount of cannabis, it’s still not confirmed whether it works for heavy smokers.

Adding Zinc Directly To Your Urine Sample

Another method to produce false-negative results with Zinc is by adding it directly to your urine.

In the same 2011-research discussed in the previous section, it was seen that zinc supplements gave a successful false-positive when added directly into the urine.

Urine samples were taken from volunteers and were divided into two tubes. One was mixed with zinc sulfate solution. The tubes were checked for pH and then passed through ELISA testing for analysis.

The results showed that zinc ions were effective in masking the THC metabolites in urine.

However, this method would not work for specific urine testing techniques like GC-MS spectroscopy.

The biggest drawback is that this method is illegal and can get you into trouble.

Furthermore, Zinc produces turbidity in urine. Even though this turbidity is sometimes falsely assumed as protein residues, it can create suspicions.

A 2013 study also shows that Zinc sulfate can invalidate urine drug and alcohol testing but can be detected using the novel spot tests developed.

How to use

If you are a light smoker and want to pass the drug test, you can use the Zinc consumption method.

You must perform this method 12-18 hours before your drug test to get accurate results.

Also, do not exceed the required zinc dosage, or else you’ll have side effects (mentioned below).



Side effects

Is Zinc detectable in urine?

At the time of the 2 studies above, the researchers stated that there were no known ways of detecting Zinc when used as an adulterant in a urine test.

But a recent study indicates that today, zinc sulfate can be detected via the novel spot tests that have since been developed.

Also, it’s important to remember that when zinc sulfate is added directly to a urine sample, it causes a white precipitate that is slightly detectable.

Importantly, according to the SAMSHA guidelines, an abnormal color in urine is a telltale of adulteration. Perhaps the saving grace here is that turbidity in urine samples may arise from several factors.

Therefore, the slight color change is less likely to raise eyebrows unless there is abnormal foaming, which is only associated with detergents.

Moreover, most laboratories today still don’t test for Zinc, even with novel spot tests that may help with that.


If you are a light smoker and want to pass the drug test in the next 12-18 hours, zinc supplements can help you get through it.

They won’t help you detox THC but can mask the metabolites in your urine. Even though one research confirms the effects of Zinc on the results of drug tests, results are not guaranteed, and the method is not reliable.

Adding Zinc supplements to your urine may give false-negative results too, but it’s illegal and produces urine turbidity.

100% Success Rate for Passing Drug Tests!

Clear Choice Sub-Solution is the perfect solution for passing a drug test. It contains a clean synthetic urine that is biocide free and completely undetectable.

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Furthermore, the standard size container makes it easy to conceal, and it is unisex, so it can be used by both male and female users.

The information on this website about detox products and synthetic urines is for educational purposes only. We do not endorse or condone their illegal use. Always consider the laws in your area and the potential legal consequences. Consult with a healthcare professional before using any products. Your responsibility and well-being are paramount.